Article
An interleukin-10 promoter polymorphism may influence tumor development in renal cell carcinoma.
The Journal of urology - 1 Mar 2005
Havranek E, Howell W M, Fussell H M, Whelan J A, Whelan M A, Pandha H S
Abstract excerpt
PURPOSE: Polymorphisms in the promoter of the interleukin-10 (IL-10) gene may influence tumor development by altering the levels of IL-10 present in the serum or tumor microenvironment. In this study we looked for evidence of specific polymorphisms of the IL-10 promoter and whether lymphocyte expression of IL-10 correlates with specific genotypes. MATERIALS AND METHODS: Archival, paraffin embedded renal cell...
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