Article
Interleukin-10 polymorphisms, cancer susceptibility and prognosis.
Familial cancer - 1 Jan 2006
Howell W Martin, Rose-Zerilli Matthew J
Abstract excerpt
Interleukin-10 (IL-10) is a multifunctional cytokine with both immunosuppressive and anti-angiogenic functions and may have both tumour-promoting and -inhibiting properties. A large number of polymorphisms (primarily single nucleotide polymorphisms (SNPs)) have been identified in the IL-10 gene p...
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