Article
Interleukin-10 promoter polymorphisms and susceptibility to skin squamous cell carcinoma after renal transplantation.
The Journal of investigative dermatology - 1 Jan 2003
Alamartine Eric, Berthoux Patricia, Mariat Christophe, Cambazard Frédéric, Berthoux François
Abstract excerpt
After organ transplantation, susceptibility to cancer is multifactorial, especially for skin carcinomas. Risk factors may include genetic susceptibilities, such as the control of cytokine production. Interleukin-10 is a cytokine that is implicated in tumorigenesis, and it has been shown that polymorphisms in its gene promoter correlate with differential amounts of production. The aim of this study was to...
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