Article
Genetic variation in interleukin-10 gene and risk of oral cancer.
Clinica chimica acta; international journal of clinical chemistry - 1 Feb 2008
Yao Jin-Guang, Gao Lin-Bo, Liu Yun-Guang, Li Jun, Pang Guang-Fu
Abstract excerpt
BACKGROUND: Common genetic variants in immune and inflammatory response genes can affect the risk of developing oral cancer. Interleukin-10 (IL-10) is an immunosuppressive cytokine which may facilitate development of cancer by supporting tumor escape from the immune response. Inter-individual variations in IL-10 production were genetically contributed to polymorphisms within IL-10 promoter region. We determined...
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