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Article

Genetic Polymorphisms in IL-10 Promoter Are Associated With Smoking and Prostate Cancer Risk in African Americans.

Anticancer research - 1 Jan 2020

Abbas Muneer, Mason Tshela, Ibad Aliza, Khraiwesh Mozna, Apprey Victor, Kanaan Yasmine, Wilson Bradford, Dunston Georgia, Ricks-Santi Luisel, Brim Hassan

Abstract excerpt

BACKGROUND/AIM: Even though prostate cancer (PCa) has good prognosis, there is a discrepancy in the risk among ethnic groups, with high morbidity in African American men. Single nucleotide polymorphisms (SNPs) in interleukin 10 (IL-10) have been associated with inflammation and cancer risk. We investigated the association of five SNPs in the IL-10 promoter with clinical features such as Gleason score and smoking....

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Identifiers

PMID: 31892550
DOI: 10.21873/anticanres.13923
PMCID: PMC7731238

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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