Article
Interleukin-10 G-1082A and C-819T polymorphisms as possible molecular markers of urothelial bladder cancer.
Archives of medical research - 1 Feb 2009
Ahirwar Dinesh, Mandhani Anil, Mittal Rama Devi
Abstract excerpt
BACKGROUND AND AIMS: Interleukin-10 (IL-10) is an immunosuppressive cytokine that may promote tumor growth and metastasis in later stages of cancer development. DNA sequence variations in IL-10 gene may lead to altered production and/or activity, and this can modulate an individual's susceptibility to urothelial bladder cancer (UBC). To test this hypothesis, we investigated the association of rs 1800896 and rs...
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