Article
Association of genetic polymorphisms in the interleukin-10 promoter with risk of prostate cancer in Chinese.
BMC cancer - 24 Aug 2010
Liu Jie, Song Bao, Bai Xueli, Liu Wenjian, Li Zengjun, Wang Jialin, Zheng Yan, Wang Zhehai
Abstract excerpt
BACKGROUND: Recent studies identified an increased risk of prostate cancer (PCa) in Caucasian men harboring polymorphisms of genes involved in innate immunity and inflammation. This study was designed to assess whether single nucleotide polymorphisms in the IL-10 promoter play a role in predisposing individuals to PCa in a Chinese population. METHODS: We genotyped three SNPs of the IL-10 promoter (-1082A/G,...
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