Article
Interleukin-10 gene promoter polymorphisms and the risk of nasopharyngeal carcinoma.
Tissue antigens - 1 Jul 2007
Wei Y-S, Kuang X-H, Zhu Y-H, Liang W-B, Yang Z-H, Tai S-H, Zhao Y, Zhang L
Abstract excerpt
Genetic factors are known to be important in the development of nasopharyngeal carcinoma (NPC). Interleukin-10 (IL-10) is an immunosuppressive cytokine which may facilitate development of cancer by supporting tumor escape from the immune response. Interindividual variations in IL-10 production were genetically contributed to polymorphisms within IL-10 promoter region. The aim of this study was to determine...
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