Article
Association of interleukin-10 gene polymorphisms with breast cancer in a Chinese population.
Journal of experimental & clinical cancer research : CR - 17 Jun 2010
Kong Fanjun, Liu Jie, Liu Yongheng, Song Bao, Wang Hualing, Liu Wenchao
Abstract excerpt
BACKGROUND: Interleukin-10(IL-10) is a multifunctional cytokine with both immunosuppressive and antiangiogenic functions. Polymorphisms in the IL-10 gene promoter genetically determine interindividual differences in IL-10 production. This study was performed to determined whether polymorphisms in the IL-10 gene promoter were associated with breast cancer in a Chinese Han population. METHODS: We genotyped 315...
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