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Article

Effects of canonical Wnt signaling on dorso-ventral specification of the mouse telencephalon.

Developmental biology - 1 Mar 2005

Backman Mattias, Machon Ondrej, Mygland Line, van den Bout Christiaan Johannes, Zhong Weimin, Taketo Makoto M, Krauss Stefan

Abstract excerpt

Wnt signaling is involved in numerous processes during vertebrate CNS development. In this study, we used conditional Cre/loxP system in mouse to ablate or activate beta-catenin in the telencephalon in two time windows: before and after the onset of neurogenesis. We show that beta-catenin mediated Wnt signals are required to maintain the molecular identity of the pallium. Inactivation of beta-catenin in the...

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PMID: 15708565
DOI: 10.1016/j.ydbio.2004.12.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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