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Article

Dorsoventral patterning is established in the telencephalon of mutants lacking both Gli3 and Hedgehog signaling.

Development (Cambridge, England) - 1 Nov 2002

Rallu Murielle, Machold Robert, Gaiano Nicholas, Corbin Joshua G, McMahon Andrew P, Fishell Gord

Abstract excerpt

Considerable data suggest that sonic hedgehog (Shh) is both necessary and sufficient for the specification of ventral pattern throughout the nervous system, including the telencephalon. We show that the regional markers induced by Shh in the E9.0 telencephalon are dependent on the dorsoventral and anteroposterior position of ectopic Shh expression. This suggests that by this point in development regional...

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Identifiers

PMID: 12397105
DOI: 10.1242/dev.129.21.4963

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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