Article
Hedgehog signaling is involved in development of the neocortex.
Development (Cambridge, England) - 1 Aug 2008
Komada Munekazu, Saitsu Hirotomo, Kinboshi Masato, Miura Takashi, Shiota Kohei, Ishibashi Makoto
Abstract excerpt
Sonic hedgehog (Shh) function is essential for patterning and cell fate specification, particularly in ventral regions of the central nervous system. It is also a crucial mitogen for cerebellar granule neuron precursors and is important in maintenance of the stem cell niche in the postnatal telencephalon. Although it has been reported that Shh is expressed in the developing dorsal telencephalon, functions of Shh...
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