Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Temporal requirement for hedgehog signaling in ventral telencephalic patterning.

Development (Cambridge, England) - 1 Oct 2004

Fuccillo Marc, Rallu Murielle, McMahon Andrew P, Fishell Gord

Abstract excerpt

Hedgehog signaling is required for multiple aspects of brain development, including growth, the establishment of both dorsal and ventral midline patterning and the generation of specific cell types such as oligodendrocytes and interneurons. To identify more precisely when during development hedgehog signaling mediates these events, we directed the removal of hedgehog signaling within the brain by embryonic day 9...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Patterning
Share to Cerebral Cortex
Share to Hedgehog Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Interneurons

Share to Oligodendroglia

Share to Receptors, G-Protein-Coupled

Share to Smoothened Receptor

Share to Telencephalon

Source

Identifiers

PMID: 15371303
DOI: 10.1242/dev.01349

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Temporal requirement for hedgehog signaling in ventral telencephalic patterning.PMID 15371303Read ↗

Specific requirements of sonic hedgehog signaling during oligodendrocyte development.Semantic proximity Read ↗

Patterning of ventral telencephalon requires positive function of Gli transcription factors.Semantic proximity Read ↗

Sonic hedgehog contributes to oligodendrocyte specification in the mammalian forebrain.Semantic proximity Read ↗

Hedgehog signaling is involved in development of the neocortex.Semantic proximity Read ↗

Dorsoventral patterning is established in the telencephalon of mutants lacking both Gli3 and Hedgehog signaling.Semantic proximity Read ↗

Spatial and temporal regulation of ventral spinal cord precursor specification by Hedgehog signaling.Semantic proximity Read ↗

A critical role for sonic hedgehog signaling in the early expansion of the developing brain.Semantic proximity Read ↗

Effects of canonical Wnt signaling on dorso-ventral specification of the mouse telencephalon.Semantic proximity Read ↗

Hes genes regulate size, shape and histogenesis of the nervous system by control of the timing of neural stem cell differentiation.Semantic proximity Read ↗

Shh and Gli3 activities are required for timely generation of motor neuron progenitors.Semantic proximity Read ↗

The Sonic Hedgehog-Gli pathway regulates dorsal brain growth and tumorigenesisSemantic proximity Read ↗

The homeobox gene Gsx2 controls the timing of oligodendroglial fate specification in mouse lateral ganglionic eminence progenitors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.