Patterning of ventral telencephalon requires positive function of Gli transcription factors.

doi:10.1016/j.ydbio.2009.07.026

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Article

Patterning of ventral telencephalon requires positive function of Gli transcription factors.

Developmental biology - 1 Oct 2009

Yu Weiying, Wang Yiwei, McDonnell Kristen, Stephen Daniel, Bai C Brian

Abstract excerpt

The ability of neuroepithelial cells to generate a diverse array of neurons is influenced by locally secreted signals. In the spinal cord, Sonic Hedgehog (Shh) is known to induce distinct cell fates in a concentration-dependent manner by regulating the activities of the three Gli transcription factors in neural precursors. However, whether Gli-mediated Shh signaling is also required to induce different cell types...

Topics

Animals
Body Patterning
Embryo, Mammalian
Female
Hedgehog Proteins
Homeodomain Proteins
Kruppel-Like Transcription Factors
Male
Mice
Mice, Inbred Strains
Nerve Tissue Proteins
Neurons
Nuclear Proteins
Phenotype
Telencephalon
Thyroid Nuclear Factor 1
Transcription Factors
Zinc Finger Protein GLI1

Source

Open in PubMed

Identifiers

PMID: 19632216
DOI: 10.1016/j.ydbio.2009.07.026

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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