Article
Pax-6 regulates expression of SFRP-2 and Wnt-7b in the developing CNS.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Mar 2001
Kim A S, Anderson S A, Rubenstein J L, Lowenstein D H, Pleasure S J
Abstract excerpt
Wnt signaling regulates a wide range of developmental processes such as proliferation, cell migration, axon guidance, and cell fate determination. In this report, we studied the expression of secreted frizzled related protein-2 (SFRP-2), which codes for a putative Wnt inhibitor, in the developing nervous system. SFRP-2 is expressed in several discrete neuroepithelial domains, including the diencephalon, the...
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