Article
β-Catenin signaling specifies progenitor cell identity in parallel with Shh signaling in the developing mammalian thalamus.
Development (Cambridge, England) - 1 Aug 2012
Bluske Krista K, Vue Tou Yia, Kawakami Yasuhiko, Taketo Makoto M, Yoshikawa Kazuaki, Johnson Jane E, Nakagawa Yasushi
Abstract excerpt
Neural progenitor cells within the developing thalamus are spatially organized into distinct populations. Their correct specification is critical for generating appropriate neuronal subtypes in specific locations during development. Secreted signaling molecules, such as sonic hedgehog (Shh) and Wnts, are required for the initial formation of the thalamic primordium. Once thalamic identity is established and...
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