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Article

GABRA2 alleles moderate the subjective effects of alcohol, which are attenuated by finasteride.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Jun 2005

Pierucci-Lagha Amira, Covault Jonathan, Feinn Richard, Nellissery Maggie, Hernandez-Avila Carlos, Oncken Cheryl, Morrow A Leslie, Kranzler Henry R

Abstract excerpt

GABA(A) receptors are involved in the subjective effects of alcohol. Endogenous neuroactive steroids interact with GABA(A) receptors to mediate several behavioral effects of alcohol in rodents. Based on a haplotypic association of alcohol dependence with the gene encoding the GABA(A) receptor alpha-2 subunit (GABRA2), we examined whether GABRA2 alleles are associated with the subjective response to alcohol. We...

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Source

Identifiers

PMID: 15702134
DOI: 10.1038/sj.npp.1300688

Genes

GABRA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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