Article
GABRA2 markers moderate the subjective effects of alcohol.
Addiction biology - 1 Mar 2013
Uhart Magdalena, Weerts Elise M, McCaul Mary E, Guo Xiuqing, Yan Xiaofei, Kranzler Henry R, Li Ning, Wand Gary S
Abstract excerpt
Individual differences in subjective responses (SRs) to alcohol are moderated by genetic variants and may be risk factors for the development of alcohol use disorders. Variation in the GABA(A) α2 receptor subunit gene (GABRA2) has been associated with alcohol dependence (AD). Therefore, we examined whether individual differences in SRs, which reflect sensitivity to the effects of alcohol, are associated with...
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