Article
Effects of GABRA2 variation on physiological, psychomotor and subjective responses in the alcohol challenge twin study.
Twin research and human genetics : the official journal of the International Society for Twin Studies - 1 Apr 2008
Lind Penelope A, MacGregor Stuart, Montgomery Grant W, Heath Andrew C, Martin Nicholas G, Whitfield John B
Abstract excerpt
Multiple reports have identified variation in the GABRA2 gene as contributing to the genetic susceptibility to alcohol dependence. However, both the mechanism behind this association, and the range of alcohol-related phenotypes affected by variation in this gene, are currently undefined. Other data suggest that the risk of alcohol dependence is increased by relative insensitivity to alcohol's intoxicating...
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