Article
Role of GABRA2 in moderating subjective responses to alcohol.
Alcoholism, clinical and experimental research - 1 Mar 2011
Roh Sungwon, Matsushita Sachio, Hara Sachiko, Maesato Hitoshi, Matsui Toshifumi, Suzuki Go, Miyakawa Tomohiro, Ramchandani Vijay A, Li Ting-Kai, Higuchi Susumu
Abstract excerpt
BACKGROUND: Human twin studies have shown that certain responses to alcohol, including subjective perceptions, are genetically influenced. Previous studies have provided evidence that a low level of response to alcohol predicts future alcohol use disorders in humans. Recent genetic studies suggest an association between alcohol dependence and genetic variation in the γ-aminobutyric acid A (GABA(A)) receptor α2...
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