Article
GABA-A2 receptor subunit gene (GABRA2) polymorphisms and risk for alcohol dependence.
Journal of psychiatric research - 1 Feb 2008
Soyka M, Preuss U W, Hesselbrock V, Zill P, Koller G, Bondy B
Abstract excerpt
Gamma-aminobutyric acid (GABA) A receptors are believed to mediate some of the physiological and behavioral actions of ethanol. Recent studies have suggested that genetic variants of the GABA-A receptor alpha2 subunit gene (GABRA2) are associated with alcohol dependence. The aim of this study is to confirm and extend the role of GABRA2 haplotypes in the liability to alcohol dependence. 291 (231 male)...
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