Article
The role of GABRA2 in alcohol dependence, smoking, and illicit drug use in an Australian population sample.
Alcoholism, clinical and experimental research - 1 Oct 2008
Lind Penelope A, Macgregor Stuart, Agrawal Arpana, Montgomery Grant W, Heath Andrew C, Martin Nicholas G, Whitfield John B
Abstract excerpt
BACKGROUND: Multiple studies have shown that genetic variation in the alpha-2 subunit of the gamma-aminobutyric acid type A (GABA(A)) receptor (GABRA2) is associated with risk for alcohol dependence. Recent reports have suggested that GABRA2 may exert its influence on dependence through factors such as sensitivity to alcohol's intoxicating effects and that GABRA2 may also contribute to a common underlying genetic...
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