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Article

STK15 F31I polymorphism is associated with increased uterine cancer risk: a pilot study.

Gynecologic oncology - 1 Oct 2007

Milam Michael R, Gu Jian, Yang Hushan, Celestino Joseph, Wu Weiguo, Horwitz Irwin B, Lacour Robin A, Westin Shannon N, Gershenson David M, Wu Xifeng, Lu Karen H

Abstract excerpt

OBJECTIVE: STK15 is a serine threonine kinase which assists chromosomal separation and mitotic spindle stability through interaction with the centrosome during mitosis. We hypothesized that STK15 polymorphisms might modulate the risk of uterine cancer. METHODS: We used a hospital-based case-control study to assess the association between STK15 polymorphisms and risk of uterine cancer. Cases and controls were...

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PMID: 17599395
DOI: 10.1016/j.ygyno.2007.05.025

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