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Article

Synergistic effects of STK15 gene polymorphisms and endogenous estrogen exposure in the risk of breast cancer.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Dec 2004

Dai Qi, Cai Qiu-Yin, Shu Xiao-Ou, Ewart-Toland Amanda, Wen Wan-Qing, Balmain Allan, Gao Yu-Tang, Zheng Wei

Abstract excerpt

STK15 is a member of a family of serine/threonine kinases that act as key regulators of chromosome segregation and cytokinesis. Over expression of the STK15 gene leads to centrosome amplification, chromosomal instability, aneuploidy, and transformation. It has been reported that the 91T --> A (Phe --> Ile at codon 31) polymorphism in the STK15 gene affects the function of this gene. We hypothesized that this...

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PMID: 15598762

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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