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STK15 polymorphism and breast cancer risk in a population-based study.

Carcinogenesis - 1 Nov 2004

Egan Kathleen M, Newcomb Polly A, Ambrosone Christine B, Trentham-Dietz Amy, Titus-Ernstoff Linda, Hampton John M, Kimura Makoto T, Nagase Hiroki

Abstract excerpt

STK15 is considered a potential cancer susceptibility gene owing to its functions in normal cell mitosis. Two common coding region polymorphisms in the gene (F31I and V57I) may affect ubiquitin-dependent degradation and thus the half-life of the encoded protein. There are limited data on the relevance of these polymorphisms to population cancer rates. To examine whether functional variation in STK15 may affect...

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PMID: 15271853
DOI: 10.1093/carcin/bgh231

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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