Article
Association of the NuMA region on chromosome 11q13 with breast cancer susceptibility.
Proceedings of the National Academy of Sciences of the United States of America - 8 Feb 2005
Kammerer Stefan, Roth Richard B, Hoyal Carolyn R, Reneland Richard, Marnellos George, Kiechle Marion, Schwarz-Boeger Ulrike, Griffiths Lyn R, Ebner Florian, Rehbock Joachim, Cantor Charles R, Nelson Matthew R, Braun Andreas
Abstract excerpt
The development of breast cancer is a complex process that involves multiple genes at many stages, from initial cell cycle dysregulation to disease progression. To identify genetic variations that influence this process, we conducted a large-scale association study using a collection of German cases and controls and >25,000 SNPs located within 16,000 genes. One of the loci identified was located on chromosome...
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