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Article

A 7 Mb region within 11q13 may contain a high penetrance gene for breast cancer.

Breast cancer research and treatment - 1 Nov 2009

Rosa-Rosa Juan Manuel, Pita Guillermo, González-Neira Anna, Milne Roger L, Fernandez Victoria, Ruivenkamp Claudia, van Asperen Christi J, Devilee Peter, Benitez Javier

Abstract excerpt

Familial breast cancer represents up to 5% of all breast cancer cases. Recently, our group has performed a new SNP-based linkage study in 19 non-BRCA1/2 families. We found that a single family was linked to regions in two different chromosomes (11q13 and 14q21), and observed a non-parametric LOD score of 11.5 in both regions. In the present study, we ruled out any possible translocation between the chromosomes....

Read the complete abstract on PubMed

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Share to Chromosomes, Human, Pair 11

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Genes, Neoplasm

Share to In Situ Hybridization, Fluorescence

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Source

Identifiers

PMID: 19205878
DOI: 10.1007/s10549-009-0317-1

Genes

BRCA1
CCND1
FADD
FGF3
FOXA1
NUMA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A 7 Mb region within 11q13 may contain a high penetrance gene for breast cancer.PMID 19205878Read ↗

Association of the NuMA region on chromosome 11q13 with breast cancer susceptibility.Semantic proximity Read ↗

Detailed map of a region commonly amplified at 11q13→q14 in human breast carcinomaSemantic proximity Read ↗

11q13 is a susceptibility locus for hormone receptor positive breast cancer.Semantic proximity Read ↗

Somatic deletions in hereditary breast cancers implicate 13q21 as a putative novel breast cancer susceptibility locus.Semantic proximity Read ↗

Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13.Semantic proximity Read ↗

Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers.Semantic proximity Read ↗

HapMap-based study of the 17q21 ERBB2 amplicon in susceptibility to breast cancer.Semantic proximity Read ↗

Coding regions of INHBA, SFRP4 and HOXA10 are not implicated in familial endometriosis linked to chromosome 7p13-15.Semantic proximity Read ↗

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Amplification of chromosome band 11q13 and a role for cyclin D1 in human breast cancerSemantic proximity Read ↗

Patterns of dna amplification at band q13 of chromosome 11 in human breast cancerSemantic proximity Read ↗

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