Article
A 7 Mb region within 11q13 may contain a high penetrance gene for breast cancer.
Breast cancer research and treatment - 1 Nov 2009
Rosa-Rosa Juan Manuel, Pita Guillermo, González-Neira Anna, Milne Roger L, Fernandez Victoria, Ruivenkamp Claudia, van Asperen Christi J, Devilee Peter, Benitez Javier
Abstract excerpt
Familial breast cancer represents up to 5% of all breast cancer cases. Recently, our group has performed a new SNP-based linkage study in 19 non-BRCA1/2 families. We found that a single family was linked to regions in two different chromosomes (11q13 and 14q21), and observed a non-parametric LOD...
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