Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic polymorphisms in centrobin and Nek2 are associated with breast cancer susceptibility in a Chinese Han population.

Breast cancer research and treatment - 1 Nov 2012

Wang Hui, Xie Yun-Tao, Han Ji-Yuan, Ruan Yuan, Song Ai-Ping, Zheng Li-Yuan, Zhang Wei-Zao, Sajdik Constantin, Li Yan, Tian Xin-Xia, Fang Wei-Gang

Abstract excerpt

Centrosome aberrations have been suggested to cause chromosomal instability and aneuploidy, and eventually promote cancer development. The Centrobin and Nek2 proteins interact with each other and both are involved in centrosome duplication and chromosome segregation. This study aimed to investigate whether genetic polymorphisms in these two genes may affect breast cancer susceptibility in Chinese Han population...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Cycle Proteins

Share to Genetic Association Studies

Share to NIMA-Related Kinases

Share to Protein Serine-Threonine Kinases

Share to Risk Factors

Source

Identifiers

PMID: 23001753
DOI: 10.1007/s10549-012-2244-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic polymorphisms in centrobin and Nek2 are associated with breast cancer susceptibility in a Chinese Han population.PMID 23001753Read ↗

Inherited variants in the inner centromere protein (INCENP) gene of the chromosomal passenger complex contribute to the susceptibility of ER-negative breast cancer.Semantic proximity Read ↗

Significance of centromere protein genes and their associated immune and metabolic differences in the prediction of prognosis and treatment outcome in breast cancerSemantic proximity Read ↗

Coding variants in the PCNT and CEP295 genes contribute to breast cancer risk in Chinese women.Semantic proximity Read ↗

Activated interferon signaling by down-regulation of CENP-N contributing to inhibited tumor growth in breast cancerSemantic proximity Read ↗

Centrosome-related genes, genetic variation, and risk of breast cancer.Semantic proximity Read ↗

Association of genetic variation in mitotic kinases with breast cancer risk.Semantic proximity Read ↗

New insights of the correlation between AXIN2 polymorphism and cancer risk and susceptibility: evidence from 72 studies.Semantic proximity Read ↗

Abnormal expression of Nek2 and β-catenin in breast carcinoma: clinicopathological correlationsSemantic proximity Read ↗

Genetic variation in the major mitotic checkpoint genes does not affect familial breast cancer risk.Semantic proximity Read ↗

Prognostic significance of centromere 17 copy number gain in breast cancer depends on breast cancer subtype.Semantic proximity Read ↗

Association of the NuMA region on chromosome 11q13 with breast cancer susceptibility.Semantic proximity Read ↗

AXIN2 Polymorphisms, the β-Catenin Destruction Complex Expression Profile and Breast Cancer Susceptibility.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.