Article
Comprehensive analysis of NuMA variation in breast cancer.
BMC cancer - 10 Mar 2008
Kilpivaara Outi, Rantanen Matias, Tamminen Anitta, Aittomäki Kristiina, Blomqvist Carl, Nevanlinna Heli
Abstract excerpt
BACKGROUND: A recent genome wide case-control association study identified NuMA region on 11q13 as a candidate locus for breast cancer susceptibility. Specifically, the variant Ala794Gly was suggested to be associated with increased risk of breast cancer. METHODS: In order to evaluate the NuMa gene for breast cancer susceptibility, we have here screened the entire coding region and exon-intron boundaries of NuMa...
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