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Article

Genetic Segregation of Spontaneous Erosive Arthritis and Generalized Autoimmune Disease in the BXD2 Recombinant Inbred Strain of Mice

31 Jan 2005

Abstract excerpt

The BXD2 strain of mice is one of approximately 80 BXD recombinant inbred (RI) mouse strains derived from an intercross between C57BL/6J (B6) and DBA/2J (D2) strains. We have discovered that adult BXD2 mice spontaneously develop generalized autoimmune disease, including glomerulonephritis (GN), increased serum titres of rheumatoid factor (RF) and anti-DNA antibody, and a spontaneous erosive arthritis...

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PMID: 15683449
DOI: 10.1111/j.0300-9475.2005.01548.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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