Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic control of spontaneous arthritis in a four-way advanced intercross line.

PloS one - 1 Jan 2013

Ranea Laura Mellado, de Castro Marques Andreia, Möller Steffen, Gupta Yask, Ibrahim Saleh M

Abstract excerpt

Identifying the genetic basis of complex diseases, such as rheumatoid arthritis, remains a challenge that requires experimental models to reduce the genetic and environmental variability. Numerous loci for arthritis have been identified in induced animal models; however, few spontaneous models have been genetically studied. Therefore, we generated a four-way advanced intercross line (AIL) from four inbred...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arthritis, Experimental
Share to Arthritis, Rheumatoid
Share to Autoimmunity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Mammalian

Share to Crosses, Genetic

Share to Mice, Transgenic

Share to Molecular Sequence Annotation

Share to Quantitative Trait Loci

Source

Open in PubMed Open full text

Identifiers

PMID: 24146764
DOI: 10.1371/journal.pone.0075611
PMCID: PMC3795728

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic control of spontaneous arthritis in a four-way advanced intercross line.PMID 24146764Read ↗

Dissecting the genetic basis of rheumatoid arthritis in mouse models.Semantic proximity Read ↗

High resolution mapping of Cia3: a common arthritis quantitative trait loci in different species.Semantic proximity Read ↗

Identification of new loci controlling collagen-induced arthritis in mouse using a partial advanced intercross and congenic strains.Semantic proximity Read ↗

Contribution of genetic studies in rodent models of autoimmune arthritis to understanding and treatment of rheumatoid arthritis.Semantic proximity Read ↗

High-resolution mapping of a complex disease, a model for rheumatoid arthritis, using heterogeneous stock mice.Semantic proximity Read ↗

Identification of epistasis through a partial advanced intercross reveals three arthritis loci within the Cia5 QTL in mice.Semantic proximity Read ↗

Identification and isolation of dominant susceptibility loci for pristane-induced arthritis.Semantic proximity Read ↗

Genetic analysis of collagen-induced arthritis in rats: a polygenic model for rheumatoid arthritis predicts a common framework of cross-species inflammatory/autoimmune disease loci.Semantic proximity Read ↗

Fine mapping of collagen-induced arthritis quantitative trait loci in an advanced intercross line.Semantic proximity Read ↗

Identification of chromosome intervals from 129 and C57BL/6 mouse strains linked to the development of systemic lupus erythematosus.Semantic proximity Read ↗

Identification of genes controlling collagen-induced arthritis in mice: striking homology with susceptibility loci previously identified in the rat.Semantic proximity Read ↗

Rheumatoid arthritis: identifying and characterising polymorphisms using rat models.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.