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Article

AMPK, the metabolic syndrome and cancer.

Trends in pharmacological sciences - 1 Feb 2005

Luo Zhijun, Saha Asish K, Xiang Xiaoqin, Ruderman Neil B

Abstract excerpt

The fuel-sensing enzyme 5'-AMP-activated protein kinase (AMPK) has a major role in the regulation of cellular lipid and protein metabolism in response to stimuli such as exercise, changes in fuel availability and the adipocyte-derived hormones leptin and adiponectin. Recent studies indicate that abnormalities in cellular lipid metabolism are involved in the pathogenesis of the metabolic syndrome, possibly because...

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Identifiers

PMID: 15681023
DOI: 10.1016/j.tips.2004.12.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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