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Article

[Aurora kinases and cancer].

Gan to kagaku ryoho. Cancer & chemotherapy - 1 Jan 2005

Kimura Masashi, Okano Yukio

Abstract excerpt

Aurora kinases are highly conserved in eukaryotes and involved in many processes during cell division. Three Aurora kinases have been identified in humans and designated as Aurora-A, -B, and -C. Aurora A regulates centrosome function during M phase through its interactions with various cell cycle regulators including TACC, chTOG, Ajuba, BRCA1, LATS2, and p53. Aurora-B localizes at the kinetochore from G2 to...

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Source

Identifiers

PMID: 15675572

Genes

BRCA1
INCENP
LATS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Targeting AURKA in Cancer: molecular mechanisms and opportunities for Cancer therapySemantic proximity Read ↗

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Aurora Kinase B Inhibition: A Potential Therapeutic Strategy for CancerSemantic proximity Read ↗

Functional Significance of Aurora Kinases–p53 Protein Family Interactions in CancerSemantic proximity Read ↗

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