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Functional Significance of Aurora Kinases–p53 Protein Family Interactions in Cancer

24 Nov 2016

Abstract excerpt

Aurora kinases play critical roles in regulating spindle assembly, chromosome segregation, and cytokinesis to ensure faithful segregation of chromosomes during mitotic cell division cycle. Molecular and cell biological studies have revealed that Aurora kinases, at physiological levels, orchestrate complex sequential cellular processes at distinct subcellular locations through functional interactions with its...

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Identifiers

PMID: 27933271
DOI: 10.3389/fonc.2016.00247

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