Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Roles of Aurora kinases in mitosis and tumorigenesis.

Molecular cancer research : MCR - 1 Jan 2007

Fu Jingyan, Bian Minglei, Jiang Qing, Zhang Chuanmao

Abstract excerpt

Aurora kinases, which have been implicated in several vital events in mitosis, represent a protein kinase family highly conserved during evolution. The activity of Aurora kinases is delicately regulated, mainly by phosphorylation and degradation. Deregulation of Aurora kinase activity can result in mitotic abnormality and genetic instability, leading to defects in centrosome function, spindle assembly, chromosome...

Topics

Join the communities discussing this publication.

Aurora Kinases
Cell Division
Chromosome Segregation
Gene Expression Regulation, Neoplastic
Mitosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Models, Biological

Protein Serine-Threonine Kinases

Source

Identifiers

PMID: 17259342
DOI: 10.1158/1541-7786.MCR-06-0208

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Roles of Aurora kinases in mitosis and tumorigenesis.PMID 17259342Read ↗

Aurora Kinases: Their Role in Cancer and Cellular ProcessesSemantic proximity Read ↗

Aurora Kinases: New Targets for Cancer TherapySemantic proximity Read ↗

Aurora Kinases and Potential Medical Applications of Aurora Kinase Inhibitors: A ReviewSemantic proximity Read ↗

The Aurora kinases: role in cell transformation and tumorigenesis.Semantic proximity Read ↗

Targeting AURKA in Cancer: molecular mechanisms and opportunities for Cancer therapySemantic proximity Read ↗

Aurora kinases signaling in cancer: from molecular perception to targeted therapiesSemantic proximity Read ↗

Aurora-A Kinase as a Promising Therapeutic Target in CancerSemantic proximity Read ↗

Functional Significance of Aurora Kinases–p53 Protein Family Interactions in CancerSemantic proximity Read ↗

Biology of Aurora A kinase: Implications in cancer manifestation and therapySemantic proximity Read ↗

Aurora kinases link chromosome segregation and cell division to cancer susceptibility.Semantic proximity Read ↗

Aurora kinase inhibitors: Progress towards the clinicSemantic proximity Read ↗

[Aurora kinases and cancer].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.