Article
The Aurora kinases: role in cell transformation and tumorigenesis.
Cancer metastasis reviews - 1 Dec 2003
Katayama Hiroshi, Brinkley William R, Sen Subrata
Abstract excerpt
Aurora kinases representing a novel family of serine/threonine kinases have been identified as key regulators of the mitotic cell division process. The three members of this kinase family, identified so far, referred to as Aurora-A, Aurora-B and Aurora-C kinases, are close homologues of the prototypic yeast Ipll and Drosophila aurora kinases, which are known to be involved in the regulation of centrosome...
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