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Aurora Kinases and Potential Medical Applications of Aurora Kinase Inhibitors: A Review

1 Jan 2015

Abstract excerpt

Aurora kinases (AKs) represent a novel group of serine/threonine kinases. They were originally described in 1995 by David Glover in the course of studies of mutant alleles characterized with unusual spindle pole configuration in Drosophila melanogaster. Thus far, three AKs A, B, and C have been discovered in human healthy and neoplastic cells. Each one locates in different subcellular locations and they are all...

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PMID: 26345296
DOI: 10.14740/jocmr2295w

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