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Article

Is glutamate decarboxylase 2 (GAD2) a genetic link between low birth weight and subsequent development of obesity in children?

The Journal of clinical endocrinology and metabolism - 1 Apr 2005

Meyre David, Boutin Philippe, Tounian Agnès, Deweirder Marianne, Aout Mounir, Jouret Béatrice, Heude Barbara, Weill Jacques, Tauber Maite, Tounian Patrick, Froguel Philippe

Abstract excerpt

Low birth weight is a risk factor for obesity and type 2 diabetes. The fetal insulin hypothesis proposes that low birth weight might be mediated partly by genetic factors that impair insulin secretion/sensitivity during the fetal stage, as shown for glucokinase, the ATP-sensitive K+ channel subunit Kir6.2, and the small heterodimer partner genes. Glutamic acid decarboxylase 2 gene (GAD2) overexpression impairs...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15671113
DOI: 10.1210/jc.2004-1468

Genes

GAD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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