Article
Interaction between prenatal growth and high-risk genotypes in the development of type 2 diabetes.
Diabetologia - 1 May 2009
Pulizzi N, Lyssenko V, Jonsson A, Osmond C, Laakso M, Kajantie E, Barker D J, Groop L C, Eriksson J G
Abstract excerpt
AIMS/HYPOTHESIS: Early environmental factors and genetic variants have been reported to be involved in the pathogenesis of type 2 diabetes. The aim of this study was to investigate whether there is an interaction between birthweight and common variants in the TCF7L2, HHEX, PPARG, KCNJ11, SLC30A8, IGF2BP2, CDKAL1, CDKN2A/2B and JAZF1 genes in the risk of developing type 2 diabetes. METHODS: A total of 2,003...
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