Article
Association of the -243 A-->G polymorphism of the glutamate decarboxylase 2 gene with obesity in girls with premature pubarche.
Fertility and sterility - 1 May 2009
Witchel Selma Feldman, White Carlie, Libman Ingrid
Abstract excerpt
OBJECTIVE: To test the a priori hypothesis that the frequency of a single-nucleotide polymorphism (SNP) located in the promoter region of the glutamate decarboxylase 2 (GAD2) gene (-243A-->G) would be overrepresented among children with higher body mass index (BMI) values. DESIGN: Genotype-phenotype correlation study. SETTING: University-based pediatric endocrinology practice. PATIENT(S): Eighty-seven girls with...
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