Mutations in the glucokinase gene of the fetus result in reduced birth weight.

doi:10.1038/953

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Article

Mutations in the glucokinase gene of the fetus result in reduced birth weight.

Nature genetics - 1 Jul 1998

Hattersley A T, Beards F, Ballantyne E, Appleton M, Harvey R, Ellard S

Abstract excerpt

Low birth weight and fetal thinness have been associated with non-insulin dependent diabetes mellitus (NIDDM) and insulin resistance in childhood and adulthood. It has been proposed that this association results from fetal programming in response to the intrauterine environment. An alternative ex...

Topics

Adult
Birth Weight
Embryonic and Fetal Development
Female
Genotype
Glucokinase
Humans
Infant, Low Birth Weight
Infant, Newborn
Insulin
Insulin Secretion
Mutation

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