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Article

Mutations in the glucokinase gene of the fetus result in reduced birth weight.

Nature genetics - 1 Jul 1998

Hattersley A T, Beards F, Ballantyne E, Appleton M, Harvey R, Ellard S

Abstract excerpt

Low birth weight and fetal thinness have been associated with non-insulin dependent diabetes mellitus (NIDDM) and insulin resistance in childhood and adulthood. It has been proposed that this association results from fetal programming in response to the intrauterine environment. An alternative explanation is that the same genetic influences alter both intrauterine growth and adult glucose tolerance. Fetal insulin...

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Source

Identifiers

PMID: 9662401
DOI: 10.1038/953

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutations in the glucokinase gene of the fetus result in reduced birth weight.PMID 9662401Read ↗

Mutations in the glucokinase gene of the fetus result in reduced placental weight.Semantic proximity Read ↗

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Type 2 diabetes risk alleles are associated with reduced size at birth.Semantic proximity Read ↗

The fetal insulin hypothesis: an alternative explanation of the association of low birthweight with diabetes and vascular disease.Semantic proximity Read ↗

A common haplotype of the glucokinase gene alters fasting glucose and birth weight: association in six studies and population-genetics analyses.Semantic proximity Read ↗

Influence of maternal and fetal glucokinase mutations in gestational diabetes.Semantic proximity Read ↗

The long-term impact on offspring of exposure to hyperglycaemia in utero due to maternal glucokinase gene mutations.Semantic proximity Read ↗

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