Article
Associations between KCNQ1 and ITIH4 gene polymorphisms and infant weight gain in early life.
Pediatric research - 1 Apr 2022
Zhang Yuanyuan, Mei Hong, Xu Ke, Li Chunan, Chang Ruixia, Qi Haiqin, Zhang Ya, Zhang Jianduan
Abstract excerpt
BACKGROUND: An earlier meta-analysis of genome-wide association studies in Asian populations detected five novel body mass index-associated single-nucleotide polymorphisms (SNPs), including potassium voltage-gated channel subfamily Q member 1 (KCNQ1) (rs2237892), ALDH2/MYL2 (rs671, rs12229654), ITIH4 (rs2535633), and NT5C2 (rs11191580). Whether these SNPs take effect in early life, for example, affect infant...