Article
Identification of a temperature-sensitive mutant of vaccinia virus defective in late but not intermediate gene expression.
Virology - 1 May 1992
Carpenter M S, DeLange A M
Abstract excerpt
The vaccinia virus conditional-lethal temperature-sensitive (ts) mutant tsC63 is defective in the synthesis of some but not all postreplicative proteins. Synthesis of the temporal "intermediate" class of proteins was unaffected, whereas "late" proteins were absent at the nonpermissive temperature...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cloning, Molecular
- DNA, Viral
- Electrophoresis, Polyacrylamide Gel
- Gene Expression Regulation, Viral
- Molecular Sequence Data
- Mutation
- Open Reading Frames
- Restriction Mapping
- Temperature