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Article

Identification of a temperature-sensitive mutant of vaccinia virus defective in late but not intermediate gene expression.

Virology - 1 May 1992

Carpenter M S, DeLange A M

Abstract excerpt

The vaccinia virus conditional-lethal temperature-sensitive (ts) mutant tsC63 is defective in the synthesis of some but not all postreplicative proteins. Synthesis of the temporal "intermediate" class of proteins was unaffected, whereas "late" proteins were absent at the nonpermissive temperature. At the DNA level, DNA synthesis was unaffected, but telomere resolution was severely inhibited. In order to identify...

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PMID: 1566576
DOI: 10.1016/0042-6822(92)90753-c

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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