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Article

Structure and expression of the vaccinia virus gene which prevents virus-induced breakdown of RNA.

Journal of virology - 1 Aug 1990

Pacha R F, Meis R J, Condit R C

Abstract excerpt

Three noncomplementing vaccinia virus temperature-sensitive mutants, ts4, ts22, and ts23, exhibit an abortive late phenotype characterized by the simultaneous cessation of protein synthesis, the breakdown of rRNA and viral mRNA, and an increase in intracellular concentrations of 2'-5'-linked oligoadenylates late during infection at the nonpermissive temperature (R.F. Pacha and R.C. Condit, J. Virol. 56:395-403,...

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Identifiers

PMID: 2370683
DOI: 10.1128/JVI.64.8.3853-3863.1990
PMCID: PMC249681

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