Article
Structure and expression of the vaccinia virus gene which prevents virus-induced breakdown of RNA.
Journal of virology - 1 Aug 1990
Pacha R F, Meis R J, Condit R C
Abstract excerpt
Three noncomplementing vaccinia virus temperature-sensitive mutants, ts4, ts22, and ts23, exhibit an abortive late phenotype characterized by the simultaneous cessation of protein synthesis, the breakdown of rRNA and viral mRNA, and an increase in intracellular concentrations of 2'-5'-linked olig...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Blotting, Northern
- Cell Line
- Cell Transformation, Viral
- Cloning, Molecular
- Gene Expression
- Genes, Viral
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- Oligonucleotide Probes
- Phenotype
- Protein Biosynthesis
- RNA, Messenger
- RNA, Ribosomal
- RNA, Viral