Vaccinia virus morphogenesis is blocked by a temperature-sensitive mutation in the I7 gene that encodes a virion component.

doi:10.1128/JVI.67.5.2689-2698.1993

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Article

Vaccinia virus morphogenesis is blocked by a temperature-sensitive mutation in the I7 gene that encodes a virion component.

Journal of virology - 1 May 1993

Kane E M, Shuman S

Abstract excerpt

The ts16 mutation of vaccinia virus WR (R. C. Condit, A. Motyczka, and G. Spizz, Virology 128:429-443, 1983) has been mapped by marker rescue to the I7L open reading frame located within the genomic HindIII I DNA fragment. The I7 gene encodes a 423-amino-acid polypeptide. Thermolabile growth was...

Topics

Amino Acid Sequence
DNA Topoisomerases, Type II
Genes, Viral
Molecular Sequence Data
Morphogenesis
Mutation
Sequence Analysis
Sequence Homology, Amino Acid
Vaccinia virus
Viral Core Proteins
Virion

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