Article
Quantification of the newly detected lamivudine resistant YSDD variants of Hepatitis B virus using molecular beacons.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Feb 2005
Pas Suzan D, Noppornpanth Suwanna, van der Eijk Annemiek A, de Man Robert A, Niesters Hubert G M
Abstract excerpt
A real-time based amplification assay with molecular beacons was used to detect and quantify PCR amplicons to discriminate between the newly described Lamivudine-resistant YSDD variant, a known YIDD variant and wild-type Hepatitis B virus (HBV) DNA in the YMDD region of the polymerase gene. Using this assay, we retrospectively analysed samples from two HBV chronically infected Asian twin sisters, starting 9 weeks...
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