Article
[A real-time PCR assay for the quantification of hepatitis B virus DNA and concurrent detection of YMDD motif mutations].
Mikrobiyoloji bulteni - 1 Oct 2011
Ağca Harun, Sayıner A Arzu, Sengönül Aylin, Simşek Ilkay, Akarsu Mesut
Abstract excerpt
Monitoring therapy in chronic hepatitis B patients receiving lamivudine therapy, is done by two different assays; determination of viral load and genotypic resistance. These methods are labor intensive and time consuming. It was aimed to develop an assay to quantitate hepatitis B virus (HBV) DNA in serum and detect YMDD (thyrosine, methionine, aspartate, aspartate) motif mutations in the same run. The assay was...
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