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Article

Measurement of paraoxonase (PON1) status as a potential biomarker of susceptibility to organophosphate toxicity.

Clinica chimica acta; international journal of clinical chemistry - 1 Feb 2005

Costa Lucio G, Cole Toby B, Vitalone Annabella, Furlong Clement E

Abstract excerpt

Organophosphorus (OP) compounds are still among the most widely used insecticides, and their main mechanism of acute toxicity is associated with inhibition of acetylcholinesterase. Measurements of urine metabolites and of blood cholinesterase activity are established biomarkers of exposure to OPs and of early biological effects. In recent years, increasing attention has been given to biomarkers of susceptibility...

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Source

Identifiers

PMID: 15653099
DOI: 10.1016/j.cccn.2004.09.019

Genes

PON1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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