Article
Effect of organophosphate intoxication on human serum paraoxonase.
Human & experimental toxicology - 1 May 2002
Sözmen E Y, Mackness B, Sözmen B, Durrington P, Girgin F K, Aslan L, Mackness M
Abstract excerpt
Recently, interindividual variations in serum paraoxonase (PON1) activity and the differences in its metabolic activity towards different organophosphates (OPs) caused by the coding region polymorphisms L55M and Q192R have been found to be important risk factors in susceptibility to OP poisoning. In this study, we investigated the effect of PON1 on the outcome of acute OP intoxication and the effect of acute OP...
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