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Activity and determinants of cholinesterases and paraoxonase-1 in blood of workers exposed to non-cholinesterase inhibiting pesticides.

Chemico-biological interactions - 25 Nov 2016

Lozano-Paniagua David, Gómez-Martín Antonio, Gil Fernando, Parrón Tesifón, Alarcón Raquel, Requena Mar, Lacasaña Marina, Hernández Antonio F

Abstract excerpt

Pesticide exposure has been associated with different adverse health effects which may be modulated to some extent by paraoxonase-1 (PON1) activity and genetic polymorphisms. This study assessed seasonal variations in PON1 activity (using paraoxon -POase-, phenylacetate -AREase-, diazoxon -DZOase- and dihydrocoumarin -DHCase- as substrates), erythrocyte acetylcholinesterase (AChE) and plasma cholinesterase (using...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27062891
DOI: 10.1016/j.cbi.2016.04.008

Genes

PON1
BCHE

Variants

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